RMC-4998

RMC-4998 is a covalent tri-complex inhibitor of KRAS^G12C(ON). RMC-4998 is a molecular glue compound with good antitumor activity. RMC-4998 is able to form a ternary complex with CYPA and an activated KRAS G12C mutant.


Cat. No.: EX-A7973	Purity: 98+%

	Chemical structure of RMC-4998

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
1mg	550	In-stock
5mg	1350	In-stock
10mg	1850	In-stock
25mg	2550	In-stock
50mg	get quote	In-stock
100mg	get quote	In-stock

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CAS No.	2642037-07-6
Purity	98+%
Formula	C57H74N8O7
Mol Weight	983.2469
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Schulze, Christopher J et al. “Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS.” Science (New York, N.Y.) vol. 381,6659 (2023): 794-799.
Data Sheet	Data sheet of RMC-4998
CoA	CoA of RMC-4998


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