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Product Information:

ONC206

ONC206 is an analogue of TRAIL inducer ONC201. ONC206 is a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations. ONC206 has broad-spectrum anti-tumor activity.

Cat. No.: EX-A5759    Purity: >98%
Chemical
Chemical structure of ONC206


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg550In-stock
200mg850In-stock
500mg1285In-stock
1g1885In-stock
5g7150In-stock


CAS No.1638178-87-6
Purity>98%
FormulaC23H22F2N4O
Mol Weight408.4438
AppearanceSolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Wagner J, et al. Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212. Cell Cycle. 2017 Oct 2;16(19):1790-1799.

[2]. Varun Vijay Prabhu, et al. Potent anti-cancer activity of the imipridone ONC206: A selective dopamine D2-like receptor antagonist. AACR Annual Meeting 2017, April 1-5, 2017; Washington, DC.

CoACoA of ONC206

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