Leupetin hemisulfate

Leupeptin hemisulfate is a broad-spectrum, membrane-permeable protease inhibitor. Leupeptin hemisulfate potently inhibits serine, cysteine and threonine proteases. Leupeptin hemisulfate inhibits Mpro (the main protease of SARS-CoV-2) and also has anti-inflammatory activity.


Cat. No.: EX-A4932	Purity: >98%

	Chemical structure of Leupetin hemisulfate

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	450	In-stock
500mg	665	In-stock
1g	1050	In-stock
2g	1668	In-stock
5g	3650	In-stock
10g	5800	In-stock

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CAS No.	103476-89-7
Purity	>98%
Formula	C40H78N12O12S
Mol Weight	951.186
Appearance	solid powder
Solubility	Soluble in H2O
Shelf Life	>2 years if stored properly
Storage	Powder -20℃, sealed storage, away from moisture, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Aoyagi T, et al. Biological activities of leupeptins. J Antibiot (Tokyo). 1969 Nov;22(11):558-68. [2]. Fu L, et al. Mechanism of Microbial Metabolite Leupeptin in the Treatment of COVID-19 by Traditional Chinese Medicine Herbs. mBio. 2021 Oct 26;12(5):e0222021. [3]. Haspel J, et al. Characterization of macroautophagic flux in vivo using a leupeptin-based assay. Autophagy. 2011 Jun;7(6):629-42.
CoA	CoA of Leupetin hemisulfate

Smiles:	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O)NC(=O)C.CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O)NC(=O)C.OS(=O)(=O)O


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