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Product Information:

iHAP1

iHAP1 is an activator of Protein phosphatase 2A (PP2A) enzymes. The PP2A complex activated by iHAP1 dephosphorylates the MYBL2 transcription factor on Ser241, causing irreversible arrest of leukemia and other cancer cells in prometaphase.

Cat. No.: EX-A4126    Purity: >98%
Chemical
Chemical structure of iHAP1


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg295In-stock
100mg385In-stock
250mg525In-stock
1g785In-stock
5gGet quoteIn-stock


CAS No.105925-39-1
Purity>98%
FormulaC20H14ClNO2S
Mol Weight367.849
Appearancesolid powder
SolubilitySoluble in DMSO, not in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2 DOI:https://doi.org/10.1016/j.cell.2020.03.051
CoACoA of iHAP1
Smiles:O=C(N1C2=C(C=CC=C2)SC3=CC=C(Cl)C=C13)C4=CC=C(OC)C=C4

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