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Product Information:

MB-07811

MB-07811 (VK-2809) is a thyroid hormone receptor beta (TRB) agonist potentially for the treatment of hyperlipidemia.

Cat. No.: EX-A3394    Purity: >99%
Chemical
Chemical structure of MB-07811


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg650In-stock
25mg985In-stock
50mg1465In-stock
100mg2200In-stock
250mg3900In-stock
500mg5600In-stock


SynonymsVK-2809
CAS No.852948-13-1
Purity>99%
FormulaC28H32ClO5P
Mol Weight514.977
AppearanceSolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Fujitaki JM, Cable EE, Ito BR, Zhang BH, Hou J, Yang C, Bullough DA, Ferrero JL, van Poelje PD, Linemeyer DL, Erion MD. Preclinical pharmacokinetics of a HepDirect prodrug of a novel phosphonate-containing thyroid hormone receptor agonist. Drug Metab Dispos. 2008 Nov;36(11):2393-403. doi: 10.1124/dmd.108.021642. PubMed PMID: 18703645.

[2]. Boyer SH, Jiang H, Jacintho JD, Reddy MV, Li H, Li W, Godwin JL, Schulz WG, Cable EE, Hou J, Wu R, Fujitaki JM, Hecker SJ, Erion MD. Synthesis and biological evaluation of a series of liver-selective phosphonic acid thyroid hormone receptor agonists and their prodrugs. J Med Chem. 2008 Nov 27;51(22):7075-93. doi: 10.1021/jm800824d. PubMed PMID: 18975928.
CoACoA of MB-07811
Smiles:OC1=CC=C(CC2=C(C)C=C(OC[P@]3(OCC[C@@H](C4=CC=CC(Cl)=C4)O3)=O)C=C2C)C=C1C(C)C

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