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Product Information:

Enbezotinib

Enbezotinib, an inhibitor of RET, can inhibit the RET autophosphorylation. Enbezotinib can be used for the research of cancer.

Cat. No.: EX-A5454    Purity: >98%
Chemical
Chemical structure of Enbezotinib


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg500In-stock
25mg750In-stock
50mg1050In-stock
100mg1450In-stock
200mg1950In-stock
500mg3000In-stock


SynonymsTPX-0046
CAS No.2359649-81-1
Purity>98%
FormulaC21H21FN6O3
Mol Weight424.4282
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Drilon, Alexander & Zhai, Dayong & Rogers, Evan & Deng, Wei & Zhang, Xin & Ung, Jane & Lee, Dong & Rodon, Laura & Graber, Armin & Zimmerman, Zachary & Murray, Brion & Subbiah, Vivek. (2020). The next-generation RET inhibitor TPX-0046 is active in drug-resistant and naïve RET-driven cancer models.. Journal of Clinical Oncology. 38. 3616-3616. 10.1200/JCO.2020.38.15_suppl.3616.

[2]. ROGERS EW, et, al. Macrocyclic compounds for treating disease. WO2019126121A1.

CoACoA of Enbezotinib

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