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Product Information:

RP-3500

RP-3500 is an orally active, selective ATR kinase inhibitor (ATRi) (IC50=1.00 nM). RP-3500 shows 30-fold selectivity for ATR over mTOR (IC50=120 nM). RP-3500 has potent antitumor activity.

Cat. No.: EX-A6416    Purity: >98%
Chemical
Chemical structure of RP-3500


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg3250In-stock
250mg3900In-stock
500mg4900In-stock
1gget quoteIn-stock


SynonymsATR inhibitor 4
CAS No.2417489-10-0
Purity>98%
FormulaC21H26N6O3
Mol Weight410.4695
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Anne Roulston, et al. RP-3500: A Novel, Potent and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP Inhibitors. Mol Cancer Ther

CoACoA of RP-3500

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