Plecanatide

Plecanatide (SP-304) is a synthetic, 16-amino acid peptide with 2 disulfide bonds that is a secondin-class guanylate cyclase-C (GC-C) receptor agonist.


Cat. No.: EX-A4131	Purity: >98%

	Chemical structure of Plecanatide

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	695	In-stock
250mg	1180	In-stock
500mg	1980	In-stock
1g	2800	In-stock
5g	11200	In-stock

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Synonyms	SP-304
CAS No.	467426-54-6
Purity	>98%
Formula	C65H104N18O26S4
Mol Weight	1681.886
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. Ice bag + foam box available upon request.

Reference:	[1]. Miner, Philip B. Plecanatide for the treatment of constipation-predominant irritable bowel syndrome. Expert review of gastroenterology & hepatology vol. 14,2 (2020): 71-84. [2]. Bassotti, Gabrio et al. Plecanatide for the treatment of chronic idiopathic constipation in adult patients. Expert review of clinical pharmacology vol. 12,11 (2019): 1019-1026. [3]. Al-Salama, Zaina T, and Yahiya Y Syed. Plecanatide: First Global Approval. Drugs vol. 77,5 (2017): 593-598.
CoA	CoA of Plecanatide

Smiles:	C[C@H]1C(=O)N[C@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@H](NC(=O)CNC(=O)[C@@H](NC2=O)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)C(C)C)CC(=O)N)C(C)C)CC(C)C)CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C


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