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Product Information:

PY-60

PY-60 is a novel small molecule activator of YAP transcriptional activity (EC50=1.5 uM) via targeting annexin A2 (ANXA2). ANXA2 is a protein that directly associates with YAP at the cell membrane in response to increased cell density.

Cat. No.: EX-A7507    Purity: >98%
Chemical
Chemical structure of PY-60


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg750In-stock
100mg1200In-stock
200mg2000In-stock
500mg3200In-stock


CAS No.2765218-56-0
Purity>98%
FormulaC16H15N3O2S
Mol Weight313.374
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Shalhout, Sophia Z et al. “YAP-dependent proliferation by a small molecule targeting annexin A2.” Nature chemical biology vol. 17,7 (2021): 767-775.

CoACoA of PY-60

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