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Product Information:

Obeldesivir

GS-5245 (Obeldesivir) is a potent, orally active antiviral agent and ester prodrugs of GS-441524. GS-5245 (Obeldesivir) inhibits the replication of SARS-CoV-2 and its variants. GS-5245 can be used for SARS-CoV-2 research.

Cat. No.: EX-A6600    Purity: >98%
Chemical
Chemical structure of Obeldesivir


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg500In-stock
100mg700In-stock
250mg1100In-stock
1g2800In-stock
5gget quoteIn-stock
10gget quoteIn-stock


SynonymsGS-5245
Synonyms 2ATV006
CAS No.2647441-36-7
Purity>98%
FormulaC16H19N5O5
Mol Weight361.3526
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StorageProtect from light Powder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Mackman, Richard L et al. “Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys.” Journal of medicinal chemistry vol. 66,17 (2023): 11701-11717.

[2]. Cao L, et, al. The adenosine analog prodrug ATV006 is orally bioavailable and has preclinical efficacy against parental SARS-CoV-2 and variants. Sci Transl Med. 2022 May 17:eabm7621.

[3]. Martinez, David R et al. “Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential.” bioRxiv : the preprint server for biology 2023.06.27.546784. 28 Jun. 2023, doi:10.1101/2023.06.27.546784. Preprint.

CoACoA of Obeldesivir

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