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Product Information:

MRTX1719

MRTX1719 is a synthetic lethal inhibitor of the PRMT5/MTA complex and selectively inhibits PRMT5 activity.

Cat. No.: EX-A5505    Purity: >99% ee:>99%
Chemical
Chemical structure of MRTX1719


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg450In-stock
100mg750In-stock
250mg1250In-stock
500mg1950In-stock
1g3650In-stock
2g5800In-stock


Synonyms(R)-MRTX-1719
Synonyms 2R-MRTX-1719
CAS No.2630904-45-7
Purity>99% ee:>99%
FormulaC23H18ClFN6O2
Mol Weight464.879
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Smith, Christopher R et al. Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of MTAP-Deleted Cancers. Journal of medicinal chemistry vol. 65,3 (2022): 1749-1766.

CoACoA of MRTX1719

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