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Product Information:

Epinastine

Epinastine is a second-generation antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.

Cat. No.: EX-A4762    Purity: >98%
Chemical
Chemical structure of Epinastine


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg770In-stock
1gGet quoteIn-stock
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CAS No.80012-43-7
Purity>98%
FormulaC16H15N3
Mol Weight249.3104
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Gumieniczek A, Berecka-Rycerz A, Hubicka U, Żmudzki P, Lejwoda K, Kozyra P. Photodegradation of the H1 Antihistaminic Topical Drugs Emedastine, Epinastine, and Ketotifen and ROS Tests for Estimations of Their Potent Phototoxicity. Pharmaceutics. 2020 Jun 17;12(6):560. doi: 10.3390/pharmaceutics12060560. PMID: 32560381; PMCID: PMC7356818.

[2]. Jha M, Moshirfar M. Epinastine. 2020 Jun 5. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan–. PMID: 32491470.

[3]. Jeong SH, Jang JH, Cho HY, Lee YB. Simultaneous measurement of epinastine and its metabolite, 9,13b-dehydroepinastine, in human plasma by a newly developed ultra-performance liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic studies. Biomed Chromatogr. 2020 Sep;34(9):e4848. doi: 10.1002/bmc.4848. Epub 2020 Jun 25. PMID: 32302007.

[4]. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006–. Epinastine. 2020 Jan 20. PMID: 30000206. [5]. Jeong SH, Jang JH, Cho HY, Lee YB. Pharmacokinetic Comparison of Epinastine Using Developed Human Plasma Assays. Molecules. 2020 Jan 3;25(1):209. doi: 10.3390/molecules25010209. PMID: 31947890; PMCID: PMC6983027.
CoACoA of Epinastine
Smiles:NC1=NCC2N1C3=CC=CC=C3CC4=CC=CC=C24

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