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Product Information:

Difelikefalin

Difelikefalin (CR-845) is a peripherally restricted and selective agonist of kappa opioid receptor (KOR). Difelikefalin produces anti-inflammatory effects and has the potential in modulating pruritus in conditions such as chronic kidney disease.

Cat. No.: EX-A5855    Purity: >98%
Chemical
Chemical structure of Difelikefalin


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg585In-stock
50mg785In-stock
100mg985In-stock
200mg1385In-stock
1g1900promotion, until Dec 31, 2024
5g7485In-stock


SynonymsCR-845
Synonyms 2FE-202845
CAS No.1024828-77-0
Purity>98%
FormulaC36H53N7O6
Mol Weight679.8493
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Steven Fishbane, et al. Randomized Controlled Trial of Difelikefalin for Chronic Pruritus in Hemodialysis Patients. Kidney Int Rep. 2020 Jan 28;5(5):600-610.

[2]. Steven Fishbane, et al. A Phase 3 Trial of Difelikefalin in Hemodialysis Patients With Pruritus. N Engl J Med. 2020 Jan 16;382(3):222-232.

CoACoA of Difelikefalin

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