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Product Information:

CDKI-73

CDKI-73 (LS-007) is an orally active and highly efficacious CDK9 inhibitor. CDKI-73 down-regulates the RNAPII phosphorylation.

Cat. No.: EX-A2385    Purity: >98%
Chemical
Chemical structure of CDKI-73


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg650In-stock
100mg900In-stock
200mg1350In-stock
1g2550In-stock


CAS No.1421693-22-2
Purity>98%
FormulaC15H15FN6O2S2
Mol Weight394.447
Appearancesolid powder
SolubilityDMSO : >50mg/mL (131.87 mM)
Shelf Life>2 years if stored properly
Storage4℃, stored under nitrogen
In solvent : -80℃, 6 months; -20℃, 1 month (stored under nitrogen)
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lam F, et al. Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73. Oncotarget. 2014 Sep 15;5(17):7691-704.

[2]. Muhammed H Rahaman, et al. CDKI-73: an orally bioavailable and highly efficacious CDK9 inhibitor against acute myeloid leukemia. Invest New Drugs. 2019 Aug;37(4):625-635.

CoACoA of CDKI-73
Smiles:CNC1=NC(C)=C(S1)C1=C(F)C=NC(NC2=CC(=CC=C2)S(N)(=O)=O)=N1

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